The liver is a large, very important organ situated in the right upper quadrant of abdomen. The normal functions of the liver in the body are:
To help store nutrients from food
To break down and remove harmful chemicals from the body
To build chemicals that the body needs to stay healthy.
Hepatoblastoma: The most common type of liver cancer in children is Hepatoblastoma. it occurs most frequently in infants or very young children between 2 months and 2 year.
- Lump in the abdomen (most common)
- Reduced appetite
- nausea / vomiting
- Pain in abdomen
- Tumor markers- serum AFP
- CT scan of abdomen with Ct guided FNAC or Biopsy
- X-ray ches/CT Chest
- Complete blood count
- Biochem profile
Surgery & chemotherapy are two treatment options
Surgery: Liver resection according to the location & extent of the tumor. It will be either
- Rt hepatectomy
- Lt hepatectomy
- Extended Rt or Lt hepatectomy
- Bi or trisegmentectomy
Chemotherapy is given before or after surgery. Surgery is done either as a sandwich surgery (in between cycles of chemotherapy) or it is done at the start & then chemotherapy is given.
The drugs used in chemotherapy are